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Neurosurgery


Tumor Surgery


A brain tumor is an abnormal growth of cells within the brain, which can be cancerous (malignant) or non-cancerous (benign). It is defined as any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells, myelin-producing Schwann cells), lymphatic tissue, blood vessels), in the cranial nerves, in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors).

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Definition

A tumor is an abnormal growth caused by the uncontrolled division of cells. Benign tumors do not have the potential to spread to other parts of the body (a process called metastasis) and are curable by surgical removal. Malignant or cancerous tumors, however, may metastasize to other parts of the body and will ultimately result in death if not successfully treated by surgery and/or other methods..

Surgical removal is one of four main ways that tumors are treated. Chemotherapy, radiation therapy, and biological therapy are other treatment options. There are a number of factors used to determine which methods will best treat a tumor. Because benign tumors do not have the potential to metastasize, they are often treated successfully with surgical removal alone. Malignant tumors, however, are most often treated with a combination of surgery and chemotherapy and/or radiation therapy (in about 55% of cases). In some instances, non-curative surgery may make other treatments more effective. Debulking a cancer-making it smaller by surgical removal of a large part of it-is thought to make radiation and chemotherapy more effective.


Complete tumor removal

Once surgical removal has been decided, an oncologic surgeon will remove the tumor whole, taking with it a large section of the surrounding normal tissue. The healthy tissue is removed to minimize the risk of possible seeding.

Primary brain tumors include any tumor that starts in the brain. Primary brain tumors can arise from the brain cells, the membranes around the brain (meninges), nerves, or glands.

Tumors can directly destroy brain cells. They can also damage cells by producing inflammation, placing pressure on other parts of the brain, and increasing pressure within the skull.
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The cause of primary brain tumors is unknown. There are many possible risk factors that could play a role.
  • Radiation therapy to the brain, used to treat brain cancers, increases the risk for brain tumors up to 20 or 30 years afterwards.
  • Exposure to radiation at work or to power lines, as well as head injuries, smoking, and hormone replacement therapy have NOT yet been shown to be factors.
  • The risk of using cell phones is hotly debated. However, most recent studies have found that cell phones, cordless phones, and wireless devices are safe and do not increase the risk.
  • Some inherited conditions increase the risk of brain tumors, including neurofibromatosis, Von Hippel-Lindau syndrome, Li-Fraumeni syndrome, and Turcot syndrome.






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